Localization | Comment | Organism | GeneOntology No. | Textmining |
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Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
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ATP + 1-phosphatidyl-1D-myo-inositol 3-phosphate | Caenorhabditis elegans | the main function of PPK-3 is to mediate membrane retrieval from matured lysosomes through regulation of PtdIns(3,5)P2. Complete loss of ppk-3 function induces developmental defects characterized by embryonic lethality, whereas partial loss of function leads to growth retardation. At the cellular level, ppk-3 mutants display a striking enlargement of vacuoles positive for lysosome-associated membrane protein 1 in different tissues | ADP + 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate | - |
? |
Organism | UniProt | Comment | Textmining |
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Caenorhabditis elegans | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + 1-phosphatidyl-1D-myo-inositol 3-phosphate | the main function of PPK-3 is to mediate membrane retrieval from matured lysosomes through regulation of PtdIns(3,5)P2. Complete loss of ppk-3 function induces developmental defects characterized by embryonic lethality, whereas partial loss of function leads to growth retardation. At the cellular level, ppk-3 mutants display a striking enlargement of vacuoles positive for lysosome-associated membrane protein 1 in different tissues | Caenorhabditis elegans | ADP + 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
phosphatidylinositol phosphate kinase 3 | - |
Caenorhabditis elegans |
PIKfyve/Fab1p | - |
Caenorhabditis elegans |
PPK-3 | - |
Caenorhabditis elegans |